Cardiac CT Imaging Diagnosis of Cardiovascular Disease 2nd Ed
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Cardiovascular Interventions in Clinical Practice
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Secondhand Smoke Exposure and Cardiovascular Effects Making Sense of the Evidence
by Data suggest that exposure to secondhand smoke can result in heart disease in nonsmoking adults. Recently, progress has been made in reducing involuntary exposure to secondhand smoke through legislation banning smoking in workplaces, restaurants, and other public places. The effect of legislation to ban smoking and its effects on the cardiovascular health of nonsmoking adults, however, remains a question.Secondhand Smoke Exposure and Cardiovascular Effects reviews available scientific literature to assess the relationship between secondhand smoke exposure and acute coronary events. The authors, experts in secondhand smoke exposure and toxicology, clinical cardiology, epidemiology, and statistics, find that there is about a 25 to 30 percent increase in the risk of coronary heart disease from exposure to secondhand smoke. Their findings agree with the 2006 Surgeon General's Report conclusion that there are increased risks of coronary heart disease morbidity and mortality among men and women exposed to secondhand smoke. However, the authors note that the evidence for determining the magnitude of the relationship between chronic secondhand smoke exposure and coronary heart disease is not very strong.Public health professionals will rely upon Secondhand Smoke Exposure and Cardiovascular Effects for its survey of critical epidemiological studies on the effects of smoking bans and evidence of links between secondhand smoke exposure and cardiovascular events, as well as its findings and recommendations. 
Antithrombotic Drug Therapy in Cardiovascular Disease
by Substantial morbidity and mortality remains associated with thrombotic events has stimulated the rapid expansion of the available armamentarium to combat pathologic thrombosis. Pathologic thrombosis plays an essential role in the pathogenesis of acute coronary syndromes (ACS), ischemic complications of percutaneous coronary intervention (PCI), venous thromboembolic disease, and embolic complications of arrhythmias and various cardiomyopathies. Written by experts in the field, Antithrombotic Drug Therapy in Cardiovascular Disease carefully examines individual and various combinations of the available antithrombotic regimens including fibrinolytic agents, antiplatelet therapies (aspirin, thieneopyridines, glycoprotein IIb/IIIa inhibitors), and anticoagulant therapies (unfractionated heparin, low-molecular-weight heparins, direct thrombin inhibitors, and synthetic factor X inhibitors), non-ST-segment elevation (NSTE) ACS and ST-segment elevation myocardial infarction (STEMI). A detailed overview, Antithrombotic Drug Therapy in Cardiovascular Disease presents the evidence demonstrating the efficacy of available antithrombotic therapies in specific disease states such as atrial fibrillation, cardiomyopathy, valvular heart disease, and heparin-induced thrombocytopenia (HIT).- Sale!
Patient Specific Modeling of the Cardiovascular System Technology Driven Personalized Medicine
by Peter Hunter Computational physiology for the cardiovascular system is entering a new and exciting phase of clinical application. Biophysically based models of the human heart and circulation, based on patient-specific anatomy but also informed by po- lation atlases and incorporating a great deal of mechanistic understanding at the cell, tissue, and organ levels, offer the prospect of evidence-based diagnosis and treatment of cardiovascular disease. The clinical value of patient-specific modeling is well illustrated in application areas where model-based interpretation of clinical images allows a more precise analysis of disease processes than can otherwise be achieved. For example, Chap. 6 in this volume, by Speelman et al. , deals with the very difficult problem of trying to predict whether and when an abdominal aortic aneurysm might burst. This requires automated segmentation of the vascular geometry from magnetic re- nance images and finite element analysis of wall stress using large deformation elasticity theory applied to the geometric model created from the segmentation. The time-varying normal and shear stress acting on the arterial wall is estimated from the arterial pressure and flow distributions. Thrombus formation is identified as a potentially important contributor to changed material properties of the arterial wall. Understanding how the wall adapts and remodels its material properties in the face of changes in both the stress loading and blood constituents associated with infl- matory processes (IL6, CRP, MMPs, etc. - Sale!
Renin Angiotensin System and Cardiovascular Disease
by Experimental and clinical evidence supports the view that the activation of the renin angiotensin aldosterone system is involved in cardiovascular pathology including hypertension, heart failure, myocardial ischemia, and atherosclerosis. The present volume describes the intricacies involved in these processes, including the in?uence of prorenin/renin, angiotensin II, angiotensin (1-7), and aldosterone on cardiac and vascular functions as well as their involvement in the generation of cardiovascular diseases. Fundamental aspects like intracellular signaling, regulation of cell volume in the failing heart, and the presence of an intracrine renin angiotensin system are discussed. Moreover, the role of the mineralocorticoid receptor as an important c- ponent of the intracrine renin angiotensin system and as a regulator of extracellular action of angiotensin II is described, reinforcing the view that aldosterone inhibitors are helpful in the treatment of heart failure and hypertension. Let us hope the imp- tant topics included here motivate basic and clinical investigators and contribute to the development of new therapeutic approaches for cardiovascular diseases. We want to thank the distinguished authors and Humana Press for the opportunity to publish this important book. Walmor C. DeMello Edward Frohlich v Contents 1 Systemic Versus Local Renin Angiotensin Systems. An Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Walmor C. DeMello and Richard N. Re 2 Clinical Import of the Local Renin Angiotensin Aldosterone Systems . . . . . . . . . . . . . . . . . . . . . . . . . 7 Edward D. Frohlich 3 Renin, Prorenin, and the (Pro)Renin Receptor . . . . . . . . . . . 15 Genevieve Nguyen and Aurelie Contrepas 4 Local Renin Angiotensin Systems in the Cardiovascular System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Richard N. - Sale!
Studies on Studies on Cardiovascular Disorders
by The role of reactive oxygen species (ROS) in the cardiovascular system is Jan- faced. Whereas low concentrations of ROS are involved in variety of physiological signalling events, oxidative stress resulting from deregulated overproduction of ROS and/or impaired antioxidant defences contributes to cardiovascular disease. The actions of ROS in the cardiovascular system are a fascinating topic, not only for the basic science researcher but also for the clinician who is interested in seeking new therapies for his patients suffering from cardiovascular disease. The current book provides a comprehensive overview of the molecular mechanisms and pathoph- iological settings in which chronic and detrimental oxidative stress arises within the heart and vasculature. The book also considers currently discussed strategies in avoiding chronic redox stress resulting from exposure to risk factors or various cardiovascular interventions. The series starts with an overview by Denise de Castro Fernandes, Diego Bonatto and Francisco Laurindo of redox signaling models that could underlie the dev- opment of redox-associated cardiovascular disorders. The interactions of proteins within signalling cascades with ROS and the regulation of such interactions by the anti-oxidative capacity of the cell are discussed. Rebecca Charles, Joseph Burgoyne and Philip Eaton report on redox-mediated modi cations of proteins under ph- iological and pathophysiological conditions and the variety of post-translational oxidative modi cations that explain redox sensing and signal transduction by proteins at the molecular level. ROS are generated during embryogenesis and may be involved in the proper development of the cardiovascular system. - Sale!
Cardiotoxicity of Non Cardiovascular Drugs
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The Cardiovascular System
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Computational Cardiovascular Mechanics Modeling and Applications in Heart Failure
by Computational Cardiovascular Mechanics provides a cohesive guide to creating mathematical models for the mechanics of diseased hearts to simulate the effects of current treatments for heart failure. Clearly organized in a two part structure, this volume discusses various areas of computational modeling of cardiovascular mechanics (finite element modeling of ventricular mechanics, fluid dynamics) in addition to a description an analysis of the current applications used (solid FE modeling, CFD). Edited by experts in the field, researchers involved with biomedical and mechanical engineering will find Computational Cardiovascular Mechanics a valuable reference. - Sale!
Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems
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Cardiovascular MRI in Congenital Heart Disease
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Nanomedicine and the Cardiovascular System
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Cardiovascular Imaging
Cardiovascular Imaging, a title in the Expert Radiology Series, edited by Drs. Vincent Ho and Gautham P. Reddy, is a comprehensive 2-volume reference that covers the latest advances in this specialty. It provides richly illustrated, advanced guidance to help you overcome the full range of diagnostic, therapeutic, and interventional challenges in cardiovascular imaging and combines an image-rich, easy-to-use format with the greater depth that experienced practitioners need. Online access at www.expertconsult.com allows you to rapidly search for images and quickly locate the answers to any questions.- Access the fully searchable text online at www.expertconsult.com, along with downloadable images.
- View 5000 full-color digital images of both radiographic images and cutting-edge modalities―MR, multislice CT, ultrasonography, and nuclear medicine.
- Tap into comprehensive coverage that includes diagnostic and therapeutic options, with an emphasis on cost-effective imaging.
- Consult the experience of a diverse group of experts on cardiovascular imaging from around the globe.
- Find information quickly and easily thanks to consistent and tightly focused chapters, a full-color design, and key points boxes.
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Fetal Cardiovascular Imaging A Disease Based Approach
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Principles of Cardiovascular Radiology
by Principles of Cardiovascular Radiology—a title in the Principles of Cardiovascular Imaging series—has everything you need to successfully obtain and interpret chest X-rays. Stuart J. Hutchison—a premier cardiac imaging specialist—covers each category of cardiac conditions and provides numerous high-quality schematic and clinical images side by side for comparison. Get only the coverage you need with clinically oriented, practical information presented in a consistent format that makes finding everything quick and easy.- Focuses on clinically oriented and practical information so that you get only the coverage that you need.
- Presents material in a consistent format that makes it easy to find information.
- Provides excellent visual guidance through high-quality images that reinforce the quality of information in the text.
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Principles of Vascular Ultrasound
by Principles of Vascular and Intravascular Ultrasound—a title in the Principles of Cardiovascular Imaging series—has everything you need to successfully obtain and interpret vascular ultrasound images. Stuart J. Hutchison—a premier cardiac imaging specialist—explains the dos and don’ts of ultrasound so you get the best images and avoid artifacts. Get only the coverage you need with clinically oriented, practical information presented in a consistent format that makes finding everything quick and easy.- Focuses on clinically oriented and practical information so that you get only the coverage that you need.
- Explains how to obtain the best image quality and avoid artifacts through instructions on how to and how not to perform vascular ultrasound.
- Provides excellent visual guidance through high-quality images—many in color—that reinforce the quality of information in the text.
- Includes numerous tables with useful values and settings to help you master probe settings and measurements.
- Presents material in a consistent format that makes it easy to find information.
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Challenging Concepts in Cardiovascular Medicine Cases with Expert Commentary
by A comprehensive guide to the assessment, diagnosis, investigation and management of complex clinical scenarios in cardiovascular medicine.This book contains a series of challenging concepts in cardiovascular medicine covering all subspecialty areas including general cardiology, intervention, cardiac imaging, electrophysiology, heart failure and cardiomyopathies, cardiac devices, transplant medicine, epidemiology, heart disease in pregnancy and congenital heart disease. Each case provides an in-depth review of current practice, the application of national and international guidelines and a summary of evidence from the medical literature. Data sets, investigation results and cardiac imaging give the reader a 'real-life' sense of being in the outpatient clinic, emergency room, coronary care unit or cardiac catheterisation laboratory. Each case is punctuated by 'Clinical Tips', 'Learning Points' and 'Landmark Trial Summaries' to enhance the learning process alongside an 'Expert Commentary' written by internationally-renowned leaders in the field of cardiology. - Sale!
Cardiovascular Pharmacotherapeutics 3rd Ed
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Horizons in World Cardiovascular Research Volume 3
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MRI of Cardiovascular Malformations
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Practical Cardiovascular Pathology 3rd Edition
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Cardiovascular Effects of Inhaled Ultrafine and Nanosized Particles
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Cardiovascular Critical Care
by Remarkable improvements in cardiac survival rates have made cardiovascular critical care much more common, but no less challenging for the practitioner. This important volume draws on the skills of an expert team of editors and contributors to present a timely overview of clinical practice.The book covers the full range of the field, from pre-operative assessment and the haematological complications of cardiovascular surgery and critical care to the care of patients with:· Arrhythmias· Heart Failure· Adult Congenital Heart Disease· Mitral Valve Disease· Aortic Valve Disease· Infective Endocarditis· VasculitisThe authors also address the special problems associated with the management of conditions consequent upon pregnancy, eclampsia, and the hypertensive crisis.With high-quality illustrations and a helpful index, Cardiovascular Critical Care gives you access to information that helps you provide the best possible care to your patients. - Sale!
Atherosclerotic Cardiovascular Disease
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A Practical Approach to Cardiovascular Medicine
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A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases
by Chronic diseases are common and costly, yet they are also among the most preventable health problems. Comprehensive and accurate disease surveillance systems are needed to implement successful efforts which will reduce the burden of chronic diseases on the U.S. population. A number of sources of surveillance data--including population surveys, cohort studies, disease registries, administrative health data, and vital statistics--contribute critical information about chronic disease. But no central surveillance system provides the information needed to analyze how chronic disease impacts the U.S. population, to identify public health priorities, or to track the progress of preventive efforts.A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases outlines a conceptual framework for building a national chronic disease surveillance system focused primarily on cardiovascular and chronic lung diseases. This system should be capable of providing data on disparities in incidence and prevalence of the diseases by race, ethnicity, socioeconomic status, and geographic region, along with data on disease risk factors, clinical care delivery, and functional health outcomes. This coordinated surveillance system is needed to integrate and expand existing information across the multiple levels of decision making in order to generate actionable, timely knowledge for a range of stakeholders at the local, state or regional, and national levels.The recommendations presented in A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases focus on data collection, resource allocation, monitoring activities, and implementation. The report also recommends that systems evolve along with new knowledge about emerging risk factors, advancing technologies, and new understanding of the basis for disease. This report will inform decision-making among federal health agencies, especially the Department of Health and Human Services; public health and clinical practitioners; non-governmental organizations; and policy makers, among others. - Sale!
Applications of Biotechnology in Cardiovascular Therapeutics
For physicians, surgeons, and scientists working on cardiovascular disorders, Applications of Biotechnology in Cardiovascular Therapeutics serves as an invaluable reference by collecting the essential writings of Dr. Kewal K. Jain on the topics of biotechnology as they relate to cardiovascular disease. This thorough volume includes such subjects as biotechnology and therapeutic delivery to the cardiovascular system, cell-selective targeted drug delivery, cell and gene therapies, including antisense and RNA interference, cutting-edge gene therapy approaches, as well as personalized cardiology as a way of integrating new technologies into the selection of the best possible treatment for an individual patient. Selected references from recent literature are collected for each chapter, and the text is supplemented by a variety of useful tables and figures. Comprehensive and up-to-date, Applications of Biotechnology in Cardiovascular Therapeutics will be tremendously useful for those working in life sciences and the pharmaceutical sciences, and the inclusion of some basics of cardiovascular diseases will greatly benefit nonmedical readers as well. - Sale!
Molecular Defects in Cardiovascular Disease
